Patents and Licensing

Licensing Agreements 

NuPathe

Demonstration of a long-term drug delivery implant in collaboration with Dr. Steve Siegel, formerly of the University of Pennsylvania. Transferred to Teva Pharmaceuticals.

Teva Pharmaceuticals Industries Ltd.

Teva logo

Demonstration of a long-term drug delivery subcutaneous implant comprising a physical mixture of drug and biodegradable polymer. Our journal publications on this topic date from 2002 to 2010, while the patents run from 2010 to 2018. In August 2023, Teva received FDA approval for a risperidone extended-release injectable suspension for the treatment of schizophrenia in adults. This is the first subcutaneous, long-acting formulation of risperidone.

JJ X-ray

xenocs logo

Designs for an environmental sample chamber for controlling relative humidity and temperature during in situ X-ray scattering experiments. (Review of Scientific Instruments, 83, 025112, 2012.) Subsequently, JJ X-ray combined with XENOCS, which now sells an environmental chamber with many of our design elements.

CSIRO

Polymerized ionic liquid block copolymers (exclusive license). Includes the following patents:  8,853,286; 9,365,688; 9,806,314; 10,122,001 (June 2021). See joint publication and patents with Prof. Yossef Elabd.

Patents Issued

  1. K. I. Winey, R. Haggenmueller, F. Du, U. S. Patent 7,148,269, issued December 12, 2006.
    “Interfacial polymer incorporation of nanotubes.”
  2. K. I. Winey, F. Du, R. Haggenmueller, T. Kashiwagi, U. S. Patent 7,265,175, issued September 4, 2007.
    “Flame retardant nanocomposite.”
  3. K. I. Winey, R. Haggenmueller, F. Du, W. Zhou, U. S. Patent 7,285,591, issued October 23, 2007.
    “Polymer-nanotube composites, fibers and processes.”
  4. S. J. Siegel, K. I. Winey, R. E. Gur, R. H. Lenox, U.S. Patent 7,666,445, issued February 23, 2010.
    “Polymer-based surgically implantable haloperidol delivery systems and methods for their production and use.”
  5. K. I. Winey, F. Du, R. Haggenmueller, U.S. Patent 7,759,413, issued July 20, 2010.
    “Dispersion method.”
  6. S. J. Siegel, K. I. Winey, U.S. Patent 8,221,778, issued July 17, 2012.
    “Drug-containing implants and methods of use thereof.”
  7. S. J. Siegel, K. I. Winey, U.S. Patent 8,329,203 issued December 11, 2012.
    “Drug-containing implants and methods of use thereof.”
  8. S. J. Siegel, K. I. Winey, U.S. Patent 8,741,327 issued June 3, 2014.
    “Method of maintaining therapeutic risperidone levels in a PLA:PLGA implant.”
  9. S. J. Siegel, K. I. Winey, R. E. Gur, R. H. Lenox, U.S. Patent 8,758,795 issued June 24, 2014.
    “Polymer-based surgically implantable haloperidol delivery systems and methods for their production and use.”
  10. S. J. Siegel, K. I. Winey, U.S. Patent 8,802,127 issued August 12, 2014.
    “Risperidone-containing PLA:PGA implants and methods of use thereof.”
  11. M. Moniruzzaman, K. I. Winey, J. Chattopadhyay, W. E. Billups, U.S. Patent 8,816,042 issued August 26, 2014.
    “Polyamide composites having flexible spacers”
  12. Y. A. Elabd, K. I. Winey, Y. Ye, J.-H. Choi, T.-S. S. Sharick, U.S. Patent 8,853,286 issued October 7, 2014.
    “Polymerized ionic liquid block copolymers as battery membranes”
  13. Y. A. Elabd, K. I. Winey, Y. Ye, J.-H. Choi, T.-S. S. Sharick, U.S. Patent 9,365,688 issued June 14, 2016.
    “Polymerized ionic liquid block copolymers as battery membranes”
  14. S. J. Siegel, K. I. Winey, U.S. Patent 9,439,905 issued September 13, 2016.
    “Risperidone-containing PLA:PGA implants and methods of use thereof.”
  15. S. J. Siegel, K. I. Winey, U.S. Patent 9,717,799 issued August 1, 2017.
    “Drug-containing implants and methods of use thereof.”
  16. Y. A. Elabd, K. I. Winey, Y. Ye, J.-H. Choi, T.-S. S. Sharick, U.S. Patent 9,806,314 issued October 31, 2017.
    “Polymerized ionic liquid block copolymers as battery membranes.”
  17. S. J. Siegel, K. I. Winey, U.S. Patent 9,895,447 issued February 20, 2018.
    “Drug-containing implants and methods of use thereof.”
  18. S. J. Siegel, K. I. Winey, U.S. Patent 9,925,268 issued March 27, 2018.
    “Drug-containing implants and methods of use thereof.”
  19. S. J. Siegel, K. I. Winey, U.S. Patent 9,925,268 issued October 30, 2018.
    “9-OH-risperidone controlled release composition.”
  20. Y. A. Elabd, K. I. Winey, Y. Ye, J.-H. Choi, T.-S. S. Sharick, U.S. Patent 10,122,001 issued November 6, 2018.
    “Polymerized ionic liquid block copolymers as battery membranes.”
  21. S. J. Siegel, K. I. Winey, U.S. Patent 10,736,965 issued August 11, 2020.
    “Risperidone biodegradable implant.”